The global next-generation antibody therapeutics market was valued at $1,328.3 million in 2014 and it is expected to grow at a CAGR of about 44% during the period 2015 – 2020. The global next-generation antibody therapeutics market is growing due to increasing popularity of antibody-drug conjugate (ADC) and increasing number of collaborations for R&D in next-generation antibody therapeutics. In addition, growing prevalence of chronic diseases and increase in research and development investments by various organizations for production of improved products further encourages the growth of global next-generation antibody therapeutics market. Furthermore, increase in healthcare expenditure and technological advancements in antibody therapeutics have led to the development of more efficient antibody therapeutics, which is resulting in increased demand for next-generation antibody therapeutics.
Based on technology, the Fc Engineered Antibodies market is expected to witness the highest growth (CAGR of 11%) during the forecast period. Among the therapeutic areas, the oncology segment led the global next-generation antibody therapeutics market in 2014, with the largest market size, but the autoimmune/inflammatory is expected to see the fastest growth of 46.4% CAGR, during the period 2015 – 2020.
The restraints associated with next-generation antibody therapeutics market include high cost, stringent regulatory requirements and time consuming approval process of drugs. A significant capital investment is required for the research and manufacturing of next-generation therapeutics. The manufacturing process of next-generation antibody therapeutics is very complex, as it requires specialized equipment and careful handling techniques. Next-generation antibody therapeutics is a biologic product, and thus requires specific downstream process for their production. This leads to the high cost of manufacturing next-generation antibody therapeutics.
The key companies operating in the global next-generation antibody therapeutics market include F. Hoffmann-La Roche Ltd, Seattle Genetics Inc., Pfizer Inc., ImmunoGen Inc., Amgen Inc., Biogen, Kyowa Hakko Kirin Co. Ltd., Xencor Inc., Bristol-Myers Squibb Company, AstraZeneca PLC., Dyax Corp., Takeda Pharmaceuticals Company Limited and Bayer AG.
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